The Biological Computing Company (TBC) is a San Francisco-based startup, founded in 2022 by neurosurgeon-neuroscientists Alex Ksendzovsky (CEO) and Jon Pomeraniec (COO), the company is building a computing platform that positions biology as a complementary compute substrate — not a replacement for silicon, but a new layer designed to improve the efficiency, stability, and adaptability of existing AI systems.

TBC's core platform encodes real-world data — images, video, and other signals — into living neuronal cultures grown on electrode grids. The neural responses are then decoded into machine-readable representations that are mapped onto frontier AI models through modular adapters. In parallel, the company's Algorithm Discovery platform observes the computational patterns of living neural networks to extract learning principles, using those insights to inform the design of AI architectures beyond the transformer paradigm.

The company reported a 23x retained improvement in video model efficiency using its biological adapters. TBC targets compute-intensive domains including computer vision, generative video, and dynamic world models — application areas where conventional scaling has encountered economic and energy constraints. The underlying thesis is that biological neural networks, refined through billions of years of evolution, offer efficiency and generalization properties that silicon-based systems do not inherently replicate.

TBC emerged from stealth in February 2026 with a $25M seed round led by Primary Venture Partners, with participation from Builders VC, E1 Ventures, Proximity, Refactor Capital, Tusk Ventures, and Wonder Ventures. The company has opened a flagship lab in San Francisco's Mission Bay.

* Primary is an investor in The Biological Computing Company